Detecting airways obstruction from the tidal flow profile

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Detecting airways obstruction from the tidal flow profile.

The two papers in this issue from the Osler Chest Unit at Oxford University [1, 2] exploit the fact that the breathing pattern in humans is affected in characteristic ways when the pulmonary airways are obstructed. MORRIS et al. [1] examined the latter part of the tidal expiratory flow pattern in patients with varying degrees of airflow obstruction and found that the expiratory time constant co...

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Chronic Airways Obstruction

A B S T R A C T The respiratory responses to hypercapnia alone and to hypercapnia and flow-resistive loading during inspiration were studied in normal individuals and in eucapnic and hypercapnic patients with chronic airways obstruction. Responses were assessed in terms of minute ventilation and occlusion pressure (mouth pressure during airway occlusion 100 ms after the onset of inspiration). V...

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Small airways obstruction syndrome.

STUDY OBJECTIVES To clarify the significance of a functional lung pattern characterized by a decreased vital capacity (VC) and an increased residual volume (RV), but with a normal FEV1/VC ratio. SETTING A university teaching hospital. SUBJECTS Patients with bronchial asthma, pulmonary emphysema, and small airways disease, and older subjects. MEASUREMENTS Measurements of static and dynamic...

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Physiological techniques for detecting expiratory flow limitation during tidal breathing.

Patients with severe chronic obstructive pulmonary disease (COPD) often exhale along the same flow-volume curve during quiet breathing as they do during the forced expiratory vital capacity manoeuvre, and this has been taken as an indicator of expiratory flow limitation at rest (EFL(T)). Therefore, EFL(T), namely attainment of maximal expiratory flow during tidal expiration, occurs when an incr...

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Assessment of upper airways obstruction.

An indication of obstruction to the upper airways (trachea and larynx) may be obtained by calculating the ratio of the forced expired volume in one second to the peak expiratory flow rate (FEV(1)/PEFR). This index was found to be usually less than 10 in normal subjects (mean 7.3), and in patients with asthma (mean 6.9), chronic bronchitis (mean 7.7), or interstitial lung disease (mean 6.3). A s...

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ژورنال

عنوان ژورنال: European Respiratory Journal

سال: 1998

ISSN: 0000-0000,0903-1936

DOI: 10.1183/09031936.98.12051008